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American Pickers star Frank Fritz suffers STROKE & remains in hospital

Frank Fritz, best known for his work on "American Pickers," is in serious health trouble... he's in the hospital after suffering a stroke.

Mike Wolfe, Frank's former History channel show co-star, has asked for thoughts and prayers for Frank's condition.

Mike shared Frank's health update Thursday on social media, saying ... "Now is the time to pray for my friend.

Frank has suffered a stroke and is in the hospital. Please keep him in your hearts and thoughts."

Frank's longtime pal added ... "I pray more than anything that you make it through this okay. I love you buddy."

Frank recently lost 65 pounds and he was believed to be living a healthier lifestyle and avoiding alcohol.

He told The Sun last year that he checked into rehab for alcohol abuse for 77 days.

It came after his nasty split from longtime girlfriend turned ex-fiancee Diann Bankson.

The vintage enthusiast also suffers from Crohn's disease, which he has been battling for over 30 years.

Frank had been working on his own Illinois antique shop since he was let go by The History Channel.